Saptak's Diary: HIV

Sunday, April 19, 2020

Virus , Lies & A Genomic Bomb - Fact or Fiction You Decide Series 5

Virus , Lies and a Genomic bomb - Please do read the earlier series 1 to 4 in my blog

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Yesterday , In my series 4 Virus, lies and a Genomic Bomb - Part 4 I had very clearly shown the striking SIMILIARITY between SPIKE Prorein of SARS- CoV2 COVID19 and GP41 of HIV (virus).

AND , this came in today's paper

Creating a scientific firestorm across the world, French virologist and medicine Nobel laureate Luc Montagnier has claimed that SARS-CoV-2, the virus that led to the global pandemic, is “man-made” as it’s the result of an attempt to manufacture a vaccine against the AIDS virus in a Chinese laboratory.

Interviewed on a French news channel, the co-discoverer of the AIDS virus who bagged the 2008 Nobel award in medicine along with other two other scientists alleged the “presence of elements of HIV and germ of malaria in the genome of

coronavirus

is highly suspect and the characteristics of the virus could not have arisen naturally”.

KIND NOTE :

These are very tough times.

The COVID19 Pandemic has created lot of economical hazards all over the world.

Please support by buying my book

Amazon INDIA Link

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Striking Similarity with HIV

Friday, April 17, 2020

Virus,Lies and a Genomic Bomb - Fact or Fiction You Decide Part 4

Today , we will study the most harmful element of 2 viruses , #CoronaVirus and #HIV.

SPIKE PROTEIN IN CORONA VIRUS

Identification and sequencing of the virus responsible for COVID-19 (view SARS-CoV-2 protein sequence) determined that it was a novel CoV that shared 88% sequence identity with two bat-derived SARS-like CoV, suggesting it had originated in bats.

Additionally, it was shown that this CoV, which was termed 2019-nCoV or SARS-CoV-2, shared 79.5% sequence identity with SARS-CoV. The coronaviral genome encodes four major structural proteins: the spike (S) protein, nucleocapsid (N) protein, membrane (M) protein, and the envelope (E) protein.

The S protein is responsible for facilitating entry of the CoV into the target cell.

It is composed of a short intracellular tail, a transmembrane anchor, and a large ectodomain that consists of a receptor binding S1 subunit and a membrane-fusing S2 subunit.

Sequence analysis of the SARS-CoV-2 S protein genome showed that it was only 75% identical with the SARS-CoV S protein.

However, analysis of the receptor binding motif (RBM) in the S protein showed that most of the amino acid residues essential for receptor binding were conserved between SARS-CoV and SARS-CoV-2, suggesting that the 2 CoV strains use the same host receptor for cell entry.

The entry receptor utilized by SARS-CoV is Angiotensin-Converting Enzyme 2 (ACE-2).

Now , we will look into GP41 from HIV .

GP41 OF HIV

Gp41 also known as glycoprotein 41 is a subunit of the envelope protein complex of retroviruses, including human immunodeficiency virus (HIV). Gp41 is a transmembrane protein that contains several sites within its ectodomain that are required for infection of host cells.

SIMILIARITY :

Recently you must have heard this news that CORONA VIRUS Patients in India ( Rajasthan ,India ) was cured with HIV Drugs.

city-docs-cure-corona-patient-with-hiv-drugs

People then might have laughed but think twice once you read the above .

A research paper by IITd which was later withdrawn had the below conclusion :