Virus,Lies and a Genomic Bomb - Fact or Fiction You Decide Part 4

Today , we will study the most harmful element of 2 viruses , #CoronaVirus and #HIV.

SPIKE PROTEIN IN CORONA VIRUS

Identification and sequencing of the virus responsible for COVID-19 (view SARS-CoV-2 protein sequence) determined that it was a novel CoV that shared 88% sequence identity with two bat-derived SARS-like CoV, suggesting it had originated in bats.

Additionally, it was shown that this CoV, which was termed 2019-nCoV or SARS-CoV-2, shared 79.5% sequence identity with SARS-CoV. The coronaviral genome encodes four major structural proteins: the spike (S) protein, nucleocapsid (N) protein, membrane (M) protein, and the envelope (E) protein.

The S protein is responsible for facilitating entry of the CoV into the target cell. 

It is composed of a short intracellular tail, a transmembrane anchor, and a large ectodomain that consists of a receptor binding S1 subunit and a membrane-fusing S2 subunit.

Sequence analysis of the SARS-CoV-2 S protein genome showed that it was only 75% identical with the SARS-CoV S protein.

However, analysis of the receptor binding motif (RBM) in the S protein showed that most of the amino acid residues essential for receptor binding were conserved between SARS-CoV and SARS-CoV-2, suggesting that the 2 CoV strains use the same host receptor for cell entry.

 The entry receptor utilized by SARS-CoV is Angiotensin-Converting Enzyme 2 (ACE-2).


Now , we will look into GP41 from HIV .

GP41 OF HIV

Gp41 also known as glycoprotein 41 is a subunit of the envelope protein complex of retroviruses, including human immunodeficiency virus (HIV). Gp41 is a transmembrane protein that contains several sites within its ectodomain that are required for infection of host cells.

SIMILIARITY :

Recently you must have heard this news that CORONA VIRUS Patients in India ( Rajasthan ,India ) was cured with HIV Drugs.

city-docs-cure-corona-patient-with-hiv-drugs

People then might have laughed but think twice once you read the above .

A research paper by IITd which was later withdrawn had the below conclusion :

KIND NOTE :

These are very tough times.

The COVID19 Pandemic has created lot of economical hazards all over the world.

Please support by buying my book 

Amazon INDIA   Link

https://www.amazon.in/SECRET-IMMORTAL-CODE-TRILOGY-Trilogy-ebook/dp/B00FBSOPXY

Amazon US Link

https://www.amazon.com/dp/B00FBSOPXY

Read the Series Here :

Series- 1st

https://saptak-firsttry.blogspot.com/2020/04/virus-lies-and-genomic-bomb-fact-or.html?m=1

Series- 2

https://saptak-firsttry.blogspot.com/2020/04/virus-lies-and-genomic-bomb-fact-or_15.html?m=1

Series- 3

https://saptak-firsttry.blogspot.com/2020/04/virus-lies-and-genomic-bomb-fact-or_16.html?m=1

Series - 4

https://saptak-firsttry.blogspot.com/2020/04/viruslies-and-genomic-bomb-fact-or.html?m=1

Series-5

https://saptak-firsttry.blogspot.com/2020/04/virus-lies-genomic-bomb-fact-or-fiction.html?m=1

Series-6

https://saptak-firsttry.blogspot.com/2020/04/viruslies-and-genomic-bomb-fact-or_19.html?m=1

Series-7

https://saptak-firsttry.blogspot.com/2020/04/viruslies-and-genomic-bomb-fact-or_23.html?m=1

Series - 8

https://saptak-firsttry.blogspot.com/2020/04/convalescent-plasma-history-looking.html?m=1

Virus, Lies and a Genomic Bomb - Fact or Fiction You Decide - Part 3

Let's start today with some evidence and a BREAKING NEWS

The Huanan Seafood Wholesale Market in the central Chinese city of Wuhan, was shut on January 1, 2020 by Chinese authorities.

The common narrative told to us by the WHO, who got their information from Chinese authorities, is that the market was “ground zero”, or origin, of the novel coronavirus outbreak. The story has been told that the virus jumped from bats to humans, with the “patient zero” being identified as a shrimp vendor in that wet market.

But -----

Look at this GRAPH taken from the Research Reports published in Jan 2020

At least two clinical studies, published six days apart in January 2020 (January 24 and January 30, 2020) disprove this Huanan-Seafood-Wholesale-Market-was-the-origin-of-SARS-CoV-2 narrative.

The studies were prepared by top-level Chinese clinical researchers.

Next ::-

Why did US Government gave $3.7 millions of US Taxpayers money to Wuhan lab Wuhan Institute of Virology for GAIN OF FUNCTION RESEARCH on Bats? Why ?

#US #COVID2019 #coronavirus 

HIGHLIGHTS

• Experiments on lab-grown pathogens, a.k.a. "chimera viruses", had been going on for years
• 
  
• They were done through so-called gain-of-function (GOF) research comprising virologists from across the world -— US, Europe, China.
• 
  
• As early as 2015, a group of researchers has successfully created a "hybrid version of a bat coronavirus — one related to the virus that causes SARS"
• 
  
• Some of those experiments were funded with US taxpayers' money

• Scientists and ethicists have been engaged in raging debates over whether engineering lab variants of viruses with possible pandemic potential is worth the risks

• In the 21st century, genetic sequencing and engineering are the new big-power frontiers

Virus , Lies and a Genomic Bomb - Fact or Fiction You decide - Part 2

The below article is from World renowned NATURE Magazine dated back to 2015 which VERY CLEARLY says Dr.Ralph Baric & Shi Zengli's team CREATED a Novel SARS - Like Virus.

Creation of Chimeric Novel SARS- like VIRUS

The article says :

Therefore, to examine the emergence potential (that is, the potential to infect humans) of circulating bat CoVs, we built a chimeric virus encoding a novel, zoonotic CoV spike protein—from the RsSHC014-CoV sequence that was isolated from Chinese horseshoe bats1—in the context of the SARS-CoV mouse-adapted backbone.


{ What is a Chimeric Virus -  


A chimera virus is defined by the Center for Veterinary Biologics (part of the U.S. Department of Agriculture's Animal and Plant Health Inspection Service) as a "new hybrid microorganism created by joining nucleic acid fragments from two or more different microorganisms in which each of at least two of the fragments contain essential genes necessary for replication."^[1] The term chimera already referred to an individual organism whose body contained cell populations from different zygotes or an organism that developed from portions of different embryos. In mythology, a chimera is a creature such as a hippogriff or a gryphon formed from parts of different animals, thus the name for these viruses.

}

 The hybrid virus allowed us to evaluate the ability of the novel spike protein to cause disease independently of other necessary adaptive mutations in its natural backbone. Using this approach, we characterized CoV infection mediated by the SHC014 spike protein in primary human airway cells and in vivo, and tested the efficacy of available immune therapeutics against SHC014-CoV. 


-  
So the Chimeric Novel SARS like virus was created back in 2015 by a team having both US & Chinese Virologist.


DOES CHIMERIC VIRUS CAN BE USED AS BIO WEAPON ?

-  Combining two pathogenic viruses increases the lethality of the new virus^[3] which is why there have been cases where chimeric viruses have been considered for use as a bioweapon. For example, the Soviet Union's Chimera Project attempted to combine DNA from Venezuelan equine encephalitis, smallpox and Ebola virus in the late 1980s^[4]. A combination smallpox and monkeypox virus has also been studied   ( AS PER WIKIPEDIA )

KIND NOTE :

These are very tough times.

The COVID19 Pandemic has created lot of economical hazards all over the world.

Please support by buying my book 

Amazon INDIA   Link

https://www.amazon.in/SECRET-IMMORTAL-CODE-TRILOGY-Trilogy-ebook/dp/B00FBSOPXY

Amazon US Link

https://www.amazon.com/dp/B00FBSOPXY

VIRUS , LIES AND A GENOMIC BOMB - FACT OR FICTION , YOU DECIDE ?

Searching the Origin of Corona Virus -Facts or Fiction - Part 1

First thing first , I am putting forth few facts proven truthful in front of you all.

The Below Article is of 2015 , Nov 16.

lab-made-coronavirus-triggers-debate

What so SPECIAL ?

Ralph Baric and his team  engineered a virus with the surface protein of the SHC014 coronavirus, found in horseshoe bats in China, and the backbone of one that causes human-like severe acute respiratory syndrome (SARS) in mice.

IN SHORT , creation of SARS - like virus.

SO ? A lot of people who were shouting that such viruses cant be created in Lab is Untrue.

WHO was in Baric's Team ?

Shi Zhengli - The BAT WOMAN

In 2014, Shi Zhengli was involved in an investigation of bat coronaviruses, specifically gain of function experiments involving both the SARS and bat coronaviruses, a joint research of University of North Carolina and Wuhan Institute of Virology, with Ralph S. Baric as principal investigator.

Who is Shi Zhengli ?

Shi is a researcher at the Wuhan Institute of Virology (WIV), CHINA ,   in the Chinese Academy of Sciences (CAS).

Who is Ralph Baric ?

an infectious-disease researcher at the University of North Carolina, US at Chapel Hill

Who was sponsoring the Project ?

Any Guess , US .

So now you know that there's more what we see .
I am not saying anything , its all there already.

WHAT HAPPENED NEXT ?

That same year funding for the project in the US had been paused.

WHY ?

as told before , there's more what we see.

- this is part 1 , will be back with part 2 soon...till then think !

KIND NOTE :

These are very tough times.

The COVID19 Pandemic has created lot of economical hazards all over the world.

Please support by buying my book 

Amazon INDIA   Link

https://www.amazon.in/SECRET-IMMORTAL-CODE-TRILOGY-Trilogy-ebook/dp/B00FBSOPXY

Amazon US Link

https://www.amazon.com/dp/B00FBSOPXY

Read the Series Here :

Series- 1st

https://saptak-firsttry.blogspot.com/2020/04/virus-lies-and-genomic-bomb-fact-or.html?m=1

Series- 2

https://saptak-firsttry.blogspot.com/2020/04/virus-lies-and-genomic-bomb-fact-or_15.html?m=1

Series- 3

https://saptak-firsttry.blogspot.com/2020/04/virus-lies-and-genomic-bomb-fact-or_16.html?m=1

Series - 4

https://saptak-firsttry.blogspot.com/2020/04/viruslies-and-genomic-bomb-fact-or.html?m=1

Series-5

https://saptak-firsttry.blogspot.com/2020/04/virus-lies-genomic-bomb-fact-or-fiction.html?m=1

Series-6

https://saptak-firsttry.blogspot.com/2020/04/viruslies-and-genomic-bomb-fact-or_19.html?m=1

Series-7

https://saptak-firsttry.blogspot.com/2020/04/viruslies-and-genomic-bomb-fact-or_23.html?m=1

Series - 8

https://saptak-firsttry.blogspot.com/2020/04/convalescent-plasma-history-looking.html?m=1

সব মনে রাখা হবে

সব মনে রাখা হবে -
   সপ্তর্ষি বসু

সব মনে রাখা হবে ,
সব কিছু মনে রাখা হবে ,
 তুমি চেয়েছিলে শেষ করে দিতে আমাদের ,
 মহামারী এনেছিলে এই পৃথিবীর বুকে ,
  তবে জেনে রেখো আমাদের বুকে জ্বলবে আগুন
   স্মরণে যাদের তুমি ছিনিয়ে নিয়েছো ।

সব মনে রাখা হবে ,
সব কিছু মনে রাখা হবে ,
 তুমি ভেবেছিলে হারাবে আমাদের ,
    তবে জেনে রেখো ভস্ম থেকে জন্মাবো আমরা
      আগুন পাখির মতন ।

সব মনে রাখা হবে,
 সব কিছু মনে রাখা হবে
   তুমি ভেবেছিলে যুদ্ধে করবে জয় ,
    তবে আমাদের সৈনিকদের বলিদানে
    তোমার হবেই পরাজয় ।

সব মনে রাখা হবে,
সব কিছু মনে রাখা হবে
  তুমি ভেবেছিলে ভাঙবে আমাদের ঐক্য
 তবে যেন রেখো আজ সবাই এক
   হিন্দু মুসলিম শিখ ঈশাই ।

সব মনে রাখা হবে,
সব কিছু মনে রাখা হবে
তোমার অদৃশ্য হাত যতই হানুক মৃত্যুবান
মায়ের আদরে সবাইকে সুষ্ট করে তুলবে
আমাদের চিকিৎসক , মাতৃকা ।

সব মনে রাখা হবে,
সব কিছু মনে রাখা হবে
তুমি ভেবেছিলে ধ্বংস করবে আমাদের,
 সব শেষ করে দেবে ,
তবে জেনে রেখো আগামী দিনে নতুন প্রজন্ম জানবে,
হয়েছিল আমাদের জয় আর তোমার পরাজয় ।

সব মনে রাখা হবে ,
সব কিছু মনে রাখা হবে ।

The Nurse

- Saptarshi Basu

A raindrop falls, hits the ground, disintegrates and is no more.
The last light of sunlight leaves with a disappointing face.

Imagine a home in the country
Imagine a garden, rose beds
Think of the sun in the flowers,
Imagine your children playing,
As you watch the monument from a long , long distance
Isn't the air soo free of pollution ?

Schools aren’t about learning now.
Offices aren’t about working anymore.
Churches aren’t about praying now.
Restaurants aren’t about eating anymore.
Yet Gods now resides in hospitals
 fighting for our lives.

Imagine a girl who wanted to live...
Just like you and me .
Imagine a girl who wanted to be
Perhaps, just like you and me
And, as you sit now in you chair and read the morning paper ,
She is no more.

I have heard of soldiers
dying in the battlefield
I have seen the deadly smoke of world war II
this is a new war with an invisible enemy
And she fought for all of us.

And then when the war is over
And then when the invisible enemy is defeated
we all will be back to our normal chores
But She is no more .

No medals around her battered face
No gaurd of honour one last time
but time will remember her
for saving soo many lives.

KIND NOTE :

These are very tough times.

The COVID19 Pandemic has created lot of economical hazards all over the world.

Please support by buying my book 

Amazon INDIA   Link

https://www.amazon.in/SECRET-IMMORTAL-CODE-TRILOGY-Trilogy-ebook/dp/B00FBSOPXY

Amazon US Link

https://www.amazon.com/dp/B00FBSOPXY

SHADOW

Shadow ( Post COVID19 )

_ S.B. ( Saptarshi Basu )

Time has gone by , fast forward mode
 The world back to its normal senses
  Buses puffing smoke as he walked towards his office.
   There's a fresh coating everywhere,
Yet the shadow have not left him.

  A thick layer of dust has gathered to welcome him,
   Along with the old dried leaves which have fallen.
  Old , few new faces across the street corners
Yet the shadow have not left him.

    He coughs a bit as he settles in ,
       The new air not so fresh anymore.
       A strange sense of drifting clutters him
        Like a sailor who looks back to his home
  While moving far away.
   Yet the shadow have not left him.

The shoe size of the shadow misfits him
   The shirt dandling a bit more on a pale structure,
  Of the shadow.
He looks for a moment till he recognises the shadow ,
 Of his father
  The Pandemic has created holes in our heart.
Yet the shadow have not left him.

Kolkata Book Fair - Our Beloved BoiMela Memories

#BoiMela #KolkataBookFair #Boimela2020 #InternationalBookFair #KolkataInternationalBookFair

Tomorrow ( or today as it's past 12 ) is the last day of our beloved BoiMela , Kolkata International Book Fair.
    Perhaps, this is the first time that I couldn't visit even being in Kolkata.From last wednesday , down with viral fever.And though the fever has subsided now , the wreakage of severe weakness along with cold makes it impossible for me to visit tomorrow.
      Story books had always been a special person in my life.As if a close friend filing up the gap of loneliness.As a child ,I use to live in quite a humble govt.quarters .One thing which was visible almost every corner was books.My parents specially my mother  had been a voracious reader.I still remember as early as in class 5, I had started reading Rabindranath & russian literature.
      2 books which had a long lasting impact on my then fertile mind   was - (1) ইস্পাত ( How the steel was tempered) by Nikolai Ostrovsky    (2) মা ( The Mother ) by Maxim Gorky .
      I still remember with a faint smile on my face that my dear mother was not quite pleased watching me reading the above books and felt I might get into politics which was least looked into from a middle class family.
       Though I had read non-fictions but the real enjoyment I use to get then and now is in fiction.The exploration of human mind and the depth and absurdity of thoughts can be truly enjoyed in the best fiction writing.
     What more can one want or seek if he or she is given a pletora of best fiction works - Ranging from Tagore , Camus , Naipaul , Amitava ghose, Murakami, Mo Yan , Tan Twan Eng , and more and more.
        Almost like being on a vacation of the best of the best imaginations.
     My relation to kolkata book fair goes long back to my childhood days when we weren't in kolkata.Probably my Uncle carrying a book for me and my greatest delight and curiosity to finish it off first.
     Back to my BE College days wherein the BoiMela happen to be on the Maidan ground .
The smell of books , aha !
Back then the boimela hasn't turned into a gastronomic experience yet , it was more about books and the love of art.
    And then 2012 happened !
     To be honest ,I never dreamt to be a writer leave apart publishing my novel.In fact ,I started writing quite late during my Onsite days in London.
    The plenty of idle time you generally have after office outside of boozing, shopping , visiting new places and doing things which you had never thought in your hometown , there's still a vast room of loneliness which I tried to fillup by writing giberish.
  Like anything and everything.Life in Engg college , after college , Software Industry .
Etc , etc & etc.
Of Love, loathings & longings.
  And somehow in due course of time , those writings slowly transformed into a book.
  And whats more , it got published.
     Times of India stall , hall 1 , stall no. 5 .
       The very D-day when your book gets launched and what can be a better place than our Kolkata Book Fair , our Beloved BoiMela.
    So we all went.It was kind of a family get together.Me being the most nervous sort.
   Quite logically , in my entire life of utter mediocracy  till then , this was ' The Moment '. Wherein you get at least a little bit transformed from NoOne to a better NoOne.
  Whom someone might recognize.
     People started coming in.The TOI guys managing the stall smiled and welcomed me warmly.I whimmed inside the stall like a nervous deer.
    Amlan , my dear friend and my wife had already taken up the valiant act to introduce me to anyone and everyone whoever came to TOI stall.Generous people surrendered to their persuation and few even bought my book.
   Next thing , the book signing session followed.
    In all that excitement time flew devoiding Einstein's theory of relativity and it was almost the day was about to be over.
     How can you leave the boimela without having the slightest gastronomic experience.
So fish Kabiraji and frys followed.
   And so the love.

   
As I look back painfully of missing this year 's boimela , I will be deeply waiting for it the next year.
     And the year next !